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Cristina Blanco Andujar

Shape effect on heat dissipation

 Iron oxide nanoparticles have been exploited as heat vectors in magnetic hyperthermia for more than five decades. Their use in vivo in humans has been also explored with positive results, yet the quality of the particles used and the heat obtained from them was not optimal. This can be achieved by different means, such as size, composition or shape, among others. Herein, nanoparticles of different morphology have been synthesised by thermal decomposition to study the effect of shape on the heat dissipation capabilities of the NP systems. For this purpose, 4 morphologies were prepared: spheres,  cubes, octopods and platelets.

Magnetic characterisation and AC hysteresis loop measurements were carried out during the COST STSM to finalise the characterisation profile of the dendronized nanoparticles. The obtained results have shown that the morphology of NPs had a direct effect on the heat dissipation capacity of the studied system. Maximum saturation magnetisation was observed for octopod shaped NPs, which was also translated into a higher potential for magnetic hyperthermia as attested by the calorimetric measurements and the increased area of the hysteresis loops obtained by AC Magnetometry. Finally, particle size was found to have an effect on the heat dissipation of octopod shaped nanoparticles as the main mechanism of relaxation was found to shift from Néel to Brownian with the increase of particle size.