Eleni Efthimiadou

Position: Researcher


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Description:

 Dr. Eleni K. Efthimiadou completed her MSc and PhD at the University of Athens (Greece) in the domain of Chemistry and she deal with the synthesis, characterization and biological evaluation of organic and inorganic compounds and she was founded by the NCSR “Demokritos” during my PhD. The synthetic compounds, organic or inorganic, had been biological evaluated as potential new drugs, MRI contrast agents, antimicrobials and anticancer. After that, she was working for 3 years as a postdoctoral fellow at the Institute of Sol-Gel Laboratory, Institute of Nanoscience and Nanotechnology, of NCSR “Demokritos” in Athens, Greece, where she is working in the domain of Nanotechnology us potential Drug Delivery Systems (DDS).In July 2009 she started my postdoc research at the group of Prof. Dr. George Kordas at the Sol-Gel Laboratory, Institute for Advanced Materials, Physicochemical processes, Nanotechnology & Microsystems, NCSR “Demokritos” following a competitive process. She started her postdoc research in the field of Nanobiopharmaceutics within the group of Dr. G. Kordas who was one of the pioneers in the field of nanostructures. Dr. G. Kordas is recipient of an Advanced Grand ERC program named: IDEAS –NANOTHERAPY”, a novel nano-container drug carrier for targeted treatment of prostate cancer. Up to date she is working at G. Kordas lab for an additional ERC PoC grand. During this period, she worked in the development of new synthetic methods for Nanocontainers fabrication and their characterization and biological evaluation. In his laboratory, she successfully developed an efficient method to fabricate smart polymeric targeted nanocontainers (NCs) based on their functionalization. The fabricated NCs exhibit different sensitivities such as pH, Thermo and Redox or combination of them. The NCs were modified with Magnetic Nanoparticles (MNPs) with target moieties, peptides and small molecules as well as coated with different biocompatible (polyethylene Glycol, PEG) and biodegradable polymers (Polylactic Acid, PLA). I also work on the polysaccharides as advanced coated material inducing specific pH, Thermo and Redox properties in this domain.